Endocrine Abstracts

Non-alcoholic fatty liver disease (NAFLD) develops in 75–90% of patients with diabetes mellitus 2 type (DM2) and obesity (Ob). Collagen degradation is regulated by the activity of interstitial collagenases, especially matrix metalloproteinases 1 type (MMP-1). It is necessary to determine levels of tissue inhibitor of metalloproteinases-1 (TIMP-1), which regulates activity of MMP-1.Aim: Optimisation of diagnosis and specification of prognosis of NAFL...